In western society, cardiovascular disease is one of the leading causes of
death. An appropriate lifestyle and therapeutic interventions can delay the
deterioration of cardiovascular disease. As a result, early detection of
cardiovascular disease has received significant attention. Two of the oldest
cardiovascular signals measured are blood pressure [1] and ECG [2]. These
measures provide (non-) invasive estimates of cardiac and vascular function.
With technical advances, the entire arterial blood pressure waveform (figure 1)
became available to clinicians, allowing a major step forward in the recognition
of cardiovascular disease. For example, the arterial blood pressure waveform
allows for the determination of vascular stiffness, which has been shown to be
an early predictor of the development of hypertension [3] and risk for myocardial
infarction [4]. The arterial blood pressure waveform is also used in the early
detection of shock [5, 6], guiding immediate treatment with the administration of
fluids and/or vaso-active agents. Hence the evaluation of the arterial blood
pressure waveform has become part of daily clinical practice.Monday, February 13, 2012
What’s in a wave? Houwelingen, M.J. van 2011-05-11 Doctoral Thesis Cardiology
In western society, cardiovascular disease is one of the leading causes of
death. An appropriate lifestyle and therapeutic interventions can delay the
deterioration of cardiovascular disease. As a result, early detection of
cardiovascular disease has received significant attention. Two of the oldest
cardiovascular signals measured are blood pressure [1] and ECG [2]. These
measures provide (non-) invasive estimates of cardiac and vascular function.
With technical advances, the entire arterial blood pressure waveform (figure 1)
became available to clinicians, allowing a major step forward in the recognition
of cardiovascular disease. For example, the arterial blood pressure waveform
allows for the determination of vascular stiffness, which has been shown to be
an early predictor of the development of hypertension [3] and risk for myocardial
infarction [4]. The arterial blood pressure waveform is also used in the early
detection of shock [5, 6], guiding immediate treatment with the administration of
fluids and/or vaso-active agents. Hence the evaluation of the arterial blood
pressure waveform has become part of daily clinical practice.
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