MS is a chronic disease affecting the CNS with an average disease onset in the third
or fourth decade of life. Clinical symptoms are caused by changes in the motor, sensory,
visual, and autonomic systems. Most common symptoms include visual and balance
disturbances, spasticity, bladder dysfunction, pain, and fatigue. At a later disease stage,
paralysis may occur. Other symptoms are Lhermitte’s symptom, an electrical sensation
running down the spine or limbs when the neck bends, and Uhthoff phenomenon,
worsening of symptoms when the core body temperature increases.http://repub.eur.nl/res/pub/20887/101006_Kap%2C%20Yolanda%20Susanne.pdf
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