Oropharyngeal Cancer (Chapter 2)
Good tumor control but late-side effects occur e.g. dysphagia.
Quality of Life: Dysphagia (Chapters 3-6)
Dose-effects relationships in base of tongue, tonsillar fossa and
nasopharyngeal cancer are found for swallowing problems.
Quality of Lfe: Trismus (Chapter 7)
Dose-effects relationships in base of tongue and tonsillar fossa are found
for trismus problems.
Brachytherapy (Chapters 8-10)
Patient treated by brachyhterapy have better local control, disease-free
survival and overal survival than those treated with EBRT. Also BT
patients were found to have fewer swallowing problems compared with the
non-BT group of patients.
Hyperbaric Oxygen (Chapter 11)
A great benefit for the quality of life of patients was seen in patients
who were randomized for hyperbaric oxygen after radiotherapy. A
significant difference of different aspects of quality of life was seen
for H&N35 ‘swallowing problems’, H&N35 ‘sticky saliva’, H&N35
‘dry mouth’, visual analogue scale (VAS) ‘Dry mouth’, PSS
‘eating in public’ and VAS ‘pain in mouth’ in favor of the
hyperbaric oxygen group.
Non-Rigid Registration / Atlas-Based Auto-Segmentation (Chapters 12-14)
Non-rigid registration method is a powerful tool to accurately assess
local shape and position changes in HNC patients. When using ABAS, edited
auto-contours were somewhat more in concordance with the corresponding
levels of this atlas as opposed to the originally contoured levels.
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