Over the last few decades clinical cancer research has developed at accelerating speed,
resulting in a tremendous increase of knowledge with regard to tumour biology, hypotheses
to interfere with tumour growth and the subsequent development of anticancer therapies.
Obviously, the ultimate aim of cancer research is to identify treatment approaches
improving overall survival with a good quality of life. Novel anticancer therapies mostly
arise from scientifi c insights in preclinical studies, and provided that they have looked
promising in vitro and in animal models, at one point they have to be tested in humans.
Testing new cancer therapies in patients occurs in diff erent stages, i.e. successively in phase
I, phase II and phase III trials.http://repub.eur.nl/res/pub/22796/110204_Konings%2C%20Ingeborg%20Regina%20Huberta%20Maria.pdf
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