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Sunday, March 4, 2012

Sublingual immunotherapy in children with allergic rhinitis Röder, E. 2012-02-29 Doctoral Thesis

Allergic rhinitis is one of the most prevalent chronic diseases in Europe. Besides nose symptoms such as sneezing and a blocked nose, patients also suffer from general complaints like fatigue, sleeping problems and difficulty concentrating. Allergic rhinitis can have a serious impact on the daily life of children, because it interferes with their social activities, hobbies and schoolwork. Allergen avoidance and symptomatic treatment will only result in short-term relief. Allergen-specific immunotherapy on the other hand, targets the cause of the disease and can induce long-term remission of the allergic symptoms. This thesis presents an overview of the evidence for the efficacy of immunotherapy in children with allergic rhinitis and the results of the STARDROP-study. In this study the clinical efficacy, immunological effects and adherence to sublingual immunotherapy (SLIT) with a grass pollen extract in children with hay fever were investigated.
http://repub.eur.nl/res/pub/31635/120229_R%C3%B6der%2C%20Esther.pdf 

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