The large bowel can be divided into the colon, the rectosigmoid, and the
rectum. The colon starts where the small bowel ends and it is 1.5-1.8
metres long when stretched. The rectum forms the final 10-15 cm of the
large bowel, opening to the outside at the anus. The rectosigmoid is the
transitional zone between the colon and the rectum.
Colorectal cancer (CRC) is the third most frequent cancer (14%) among
males, after prostate (22%) and lung cancer (16%), and it is the second
most common tumour (13%) among females, after breast cancer (31%) in the
Netherlands. In 2007, 11,823 patients were diagnosed with CRC and 4,828
patients died of the disease. The incidence in the Netherlands is
relatively high compared to other European countries, and ranks in the
top 10.3 Worldwide, CRC accounted for about 1 million of new cancer
diagnoses in 2002, representing nearly 10% of all new cancers. It occurs
more frequently in the industrialized world. The disease rarely occurs
before age 40, and the risk of CRC becomes highest around age 70.1 It is
expected that the absolute number of patients with CRC increases with
three percent per year in the Netherlands, mainly due to the aging
population. Based on this estimation, the incidence of CRC in the
Netherlands increases to 14,000 patients in 2015. As a percentage of
total mortality, the risk of dying from CRC in the Netherlands is
highest around age 60 (about 5%), which is important because it can be
seen as an important cause of death. Later in life other causes of death
proportionally start to occur more often.http://repub.eur.nl/res/pub/19573/100527_Steenbergen%2C%20Liza%20Nicolien%20van.pdf
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