Telomeres in disease Rodrigo Calado1 and Neal Young2*

Telomeres and telomere repair are basic molecular features of cells possessing linear DNA
chromosomes and defects in them result in various diseases. This review examines recent advances in
understanding these diseases, particularly at a molecular level, and in relating telomere dysfunction to
clinical diseases. We also discuss the potential role of telomere elongation as a therapy in diseases,
and more controversially, the prevention/reversal of aging.
http://f1000.com/reports/m/4/8/pdf